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  • Diarrhea is an occasional side effect of Zelnorm . Most often, diarrhea has been reported during the first week of starting Zelnorm . Typically, diarrhea diminishes with continued therapy. If severe diarrhea, or diarrhea together with bad cramping, abdominal pain, or dizziness develops, contact your physician.
  • In studies, patients receiving Zelnorm had more abdominal surgery than patients receiving sugar pills. However, it is not known if Zelnorm will increase the risk of abdominal surgery. If you suddenly get different or worse abdominal pain, contact your physician.
  • Zelnorm increases the action of serotonin (a body chemical) in the intestines. This speeds the movement of stools (bowel movements) through the bowels.
  • Zelnorm is used to treat severe, chronic, irritable bowel syndrome (IBS) in women who have constipation as their main bowel problem (constipation-predominant). Zelnorm has not been shown to be helpful for men with irritable bowel syndrome.
  • Zelnorm may also be used for purposes other than those listed in this medication guide.




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  • Take Zelnorm exactly as directed by your physician. If you NOT understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Zelnorm should be taken twice a day on an empty stomach shortly before you eat a meal or as your physician prescribes it.
  • Zelnorm does not improve the symptoms of IBS for everyone. When Zelnorm is beneficial, it helps to reduce pain and discomfort in the abdominal area, bloating, and constipation. Some or all symptoms may improve within one to two weeks. If you NOT see any improvement in your symptoms after 4 to 6 weeks, talk to your physician.
  • Zelnorm is not a cure for irritable bowel syndrome. If you stop taking Zelnorm , symptoms may return within 1 or 2 weeks.
  • It is important to take Zelnorm regularly to get the most benefit.
  • Store Zelnorm at room temperature away from moisture and heat.

    Zelnorm side effects

  • If you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to Zelnorm , stop taking this medication and seek emergency medical attention.
  • Diarrhea is an occasional side effect of Zelnorm . Most often, diarrhea has been reported during the first week of starting Zelnorm . Typically, diarrhea diminishes with continued therapy. If severe diarrhea, or diarrhea together with bad cramping, abdominal pain, or dizziness develops, contact your physician.
  • In studies, patients receiving Zelnorm had more abdominal surgery than patients receiving sugar pills. However, it is not known if Zelnorm will increase the risk of abdominal surgery. If you suddenly get different or worse abdominal pain, contact your physician.
  • Other less serious side effects may be more likely to occur. Continue to take Zelnorm and talk to your physician if you experience
    -- headache, dizziness or migraine;
    -- back pain or joint pain; or
    -- abdominal pain, nausea or flatulence (gas).
  • Side effects other than those listed here may also occur. Talk to your physician about any side effect that seems unusual or that is especially bothersome.

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