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  • NOT stop taking this medication without first talking to your physician. If you stop taking the medication, your condition could become worse.
  • NOT crush, chew, or break extended-release forms of verapamil such as generic Covera-HS and Verelan PM. Swallow them whole. Generic verapamil SR, Isoptin SR, and Calan SR may be divided in half but should not be crushed or chewed.
  • Verapamil is in a class of drugs called calcium channel blockers. Verapamil relaxes (widens) blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.
  • Verapamil is used to treat hypertension (high blood pressure), to treat angina (chest pain), and to control some types of irregular heartbeats.
  • Verapamil may also be used for purposes other than those listed in this medication guide.




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  • Verapamil - Drug dosage. Dosage information on Verapamil

  • Take verapamil exactly as directed by your physician. If you NOT understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Verelan, Verelan PM, Calan, Isoptin, Covera-HS, and generic forms of regular-release verapamil can be taken with or without food. Taking the medication with food may reduce stomach upset if it occurs.
  • Calan SR, Isoptin SR, and generic sustained-release verapamil (verapamil SR) may be more likely to cause stomach upset and should be taken with food to reduce this side effect.
  • Take Covera-HS and Verelan PM at bedtime.
  • If you have trouble swallowing the Verelan pellet-filled capsules, they can be opened and the contents can be sprinkled onto cold, soft food such as applesauce. This mixture must be swallowed without chewing. Use the mixture immediately. NOT save it for later use. (NOT use this procedure for the Verelan PM capsules.)
  • NOT crush, chew, or break extended-release forms of verapamil such as Covera-HS and Verelan PM. Swallow them whole. Generic verapamil SR, Isoptin SR, and Calan SR may be divided in half if the tablets are scored, but should not be crushed or chewed.
  • If you are taking Covera-HS, NOT be concerned if you find what looks like an undissolved tablet in your stool. This medication is formulated with an outer shell that does not dissolve. This shell allows the medicine to be released slowly into your body before it is passed out in the stool.
  • It is important to take verapamil regularly to get the most benefit.
  • NOT stop taking this medication without first talking to your physician. If you stop taking the medication, your condition could become worse.
  • Grapefruit and grapefruit juice may interact with verapamil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your physician. NOT increase or decrease the amount of grapefruit products in your diet without first talking to your physician.
  • your physician may want you to have blood tests, blood pressure monitoring, or other medical evaluations during treatment with verapamil to monitor progress and side effects.
  • Store verapamil at room temperature away from moisture and heat.

    Verapamil side effects

  • If you experience any of the following serious side effects, stop taking verapamil and contact your physician immediately or seek emergency medical treatment:
    -- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
    -- an unusually fast or slow heartbeat;
    -- shortness of breath (heart failure);
    -- fainting;
    -- abnormal behavior or psychosis;
    -- jaundice (yellowing of the skin or eyes); or
    -- swelling of the legs or ankles.
  • Other, less serious side effects may be more likely to occur. Continue to take verapamil and talk to your physician if you experience
    -- unusual headache, fatigue, or tiredness;
    -- insomnia or trouble sleeping;
    -- vivid dreams;
    -- hair loss;
    -- nausea or diarrhea; or
    -- increased urination.
  • Side effects other than those listed here may also occur. Talk to your physician about any side effect that seems unusual or that is especially bothersome.

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