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  • Stop taking trazodone and call your physician immediately if you experience a prolonged (4 hours or longer), painful, or inappropriate erection. This could lead to a serious condition requiring surgery.
  • Use caution when driving, operating machinery, or performing other hazardous activities. Trazodone may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
  • Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
  • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking trazodone.
  • NOT stop taking trazodone without first talking to your physician, even if you begin to feel better. It may be several weeks before your symptoms begin to improve, and you may require continuous treatment for quite some time.
  • Trazodone is an antidepressant medication. It works by changing the actions of chemicals in the brain.
  • Trazodone is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide.
  • Trazodone may also be used for purposes other than those listed in this medication guide.




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  • Take trazodone exactly as directed by your physician. If you NOT understand these directions, ask your pharmacist, nurse, or doctor to explain the instructions to you.
  • Take each dose with a full glass of water.
  • Take trazodone with a meal or a light snack. Food increases the amount of medicine that is absorbed by the body and it may help to decrease dizziness.
  • NOT stop taking trazodone without first talking to your physician, even if you begin to feel better. It may be several weeks before your symptoms begin to improve, and you may require continuous treatment for quite some time.
  • Store trazodone at room temperature away from moisture and heat.

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  • If you experience any of the following serious side effects, stop taking trazodone and seek emergency medical attention or contact your physician immediately:
    -- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
    -- a prolonged (4 hours or longer), painful, or inappropriate erection; or
    -- an irregular heartbeat or chest pains.
  • Other, less serious side effects may be more likely to occur. Continue to take trazodone and talk to your physician if you experience
    -- dizziness or drowsiness;
    -- headache;
    -- insomnia or vivid dreams;
    -- dry mouth, upset stomach, nausea, or vomiting;
    -- diarrhea or constipation;
    -- tremors (shaking); or
    -- blurred vision.
  • Side effects other than those listed here may also occur. Talk to your physician about any side effect that seems unusual or that is especially bothersome.

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