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  • Seizures have been reported as a rare side effect of treatment with tramadol. The risk of seizures may be increased in patients who take more than the prescribed dose, have a history of seizures or epilepsy, have head trauma, have a metabolic disorder, have a central nervous system infection, are experiencing alcohol or drug withdrawal, or are taking certain medications. Talk to your physician about factors that may increase the risk of seizures during treatment.
  • NOT drink alcohol while taking tramadol. Alcohol may cause a dangerous decrease in breathing and/or liver problems when used during treatment with tramadol.
  • Use caution when driving, operating machinery, or performing other hazardous activities. Tramadol may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
  • NOT take more of this medication than is prescribed for you. If the pain is not being controlled, talk to your physician. Taking more than the prescribed amount of this medication could result in seizures or decreased breathing.
  • Tramadol is a pain reliever. Tramadol affects chemicals and receptors in the body that are associated with pain.
  • Tramadol is used to relieve moderate to moderately severe pain.
  • Tramadol may also be used for purposes other than those listed in this medication guide.




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  • Tramadol - Drug dosage. Dosage information on Tramadol

  • Take tramadol exactly as directed by your physician. If you NOT understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Tramadol can be taken with or without food.
  • Side effects from treatment with tramadol may be decreased by a slow increase in dose, as directed by your physician. The tablets can easily be broken in half at the score if needed. The maximum dose of tramadol for an average healthy adult is 100 mg per dose, every 4 to 6 hours, up to 400 mg per day. People over 75 years of age should not take more than 300 mg per day. People with liver or kidney disease may need lower daily doses. Follow your physician's directions.
  • NOT take more of this medication than is prescribed for you. If the pain is not being controlled, talk to your physician. Taking more than the prescribed amount of this medication could result in seizures or decreased breathing.
  • Store tramadol at room temperature away from moisture and heat.

    Tramadol side effects

  • If you experience any of the following serious side effects, stop taking tramadol and seek emergency medical attention or contact your physician immediately:
    -- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or
    -- seizures.
  • Other, less serious side effects may be more likely to occur. Continue to take tramadol and talk to your physician if you experience
    -- dizziness, drowsiness, or headache;
    -- nervousness, tremor, or anxiety;
    -- nausea, vomiting, constipation, or diarrhea; or
    -- itching, dry mouth, or sweating.
  • Tramadol is habit forming. Physical and/or psychological dependence can occur, and withdrawal effects are possible if the medication is stopped suddenly after prolonged or high-dose treatment.
  • Side effects other than those listed here may also occur. Talk to your physician about any side effect that seems unusual or that is especially bothersome.

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