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  • NOT stop taking Protonix even if you begin to feel better. Your symptoms may improve before the condition is fully treated.
  • NOT crush, chew, or split the tablets. Swallow them whole. They are specially formulated to release the medication slowly in the body.
  • Protonix decreases the amount of acid produced in the stomach.
  • Protonix is used to treat damage to the esophagus associated with gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid production (e.g. Zollinger-Ellison Syndrome).
  • Protonix may also be used for purposes other than those listed in this medication guide.




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  • Take Protonix exactly as directed by your physician. If you NOT understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Protonix can be taken with or without food.
  • NOT crush, chew, or split the tablets. Swallow them whole. They are specially formulated to release the medication slowly in the body.
  • NOT stop taking Protonix even if you begin to feel better. Your symptoms may improve before the condition is fully treated.
  • Store Protonix at room temperature away from moisture and heat.

    Protonix side effects

  • Serious side effects from Protonix are rare. Stop taking Protonix and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to Protonix.
  • Less serious side effects from Protonix are also uncommon. Continue to take Protonix and talk to your physician if you experience
    -- flatulence (gas);
    -- upset stomach or diarrhea;
    -- insomnia; or
    -- a rash.
  • Side effects other than those listed here may also occur. Talk to your physician about any side effect that seems unusual or that is especially bothersome.

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