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  • Lactic acidosis and severe liver problems, including fatal cases, have been reported with the use of Epivir, alone or in combination. Contact your physician immediately if you experience nausea, vomiting, or unusual or unexpected stomach discomfort; weakness and tiredness; shortness of breath; weakness in the arms and legs; yellowing of the skin or eyes; or pain in the upper stomach area. These may be early symptoms of lactic acidosis or liver problems.
  • Serious cases of pancreatitis (inflammation of the pancreas) have been reported with the use of Epivir. Notify your physician immediately if you develop symptoms of pancreatitis including nausea, vomiting, diarrhea, abdominal pain.
  • Avoid alcohol while taking Epivir. Alcohol may increase the risk of damage to the pancreas and/or liver.
  • Follow your physician's instructions with respect to high-risk activities such as unprotected sex and the sharing of needles. Epivir does not reduce the risk of passing the HIV or hepatitis B virus to others.
  • Epivir is an antiviral medication. It is in a category of HIV medicines called reverse transcriptase inhibitors. Epivir inhibits the reproduction of viruses in the body.
  • The Epivir brand of Epivir is used to treat the human immunodeficiency virus (HIV), which causes the acquired immunodeficiency syndrome (AIDS). The Epivir-HBV brand of Epivir is used in the treatment of chronic hepatitis B.
  • Epivir may also be used for purposes other than those listed in this medication guide.




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    • Epivir - Drug dosage. Dosage information on Epivir

  • Take Epivir exactly as directed by your physician. If you NOT understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Epivir can be taken with or without food.
  • For the treatment of HIV or AIDS, Epivir is usually taken twice a day and is often used in combination with other HIV medicines. Follow your physician's instructions.
  • For the treatment of chronic hepatitis B, Epivir is usually taken once a day. Follow your physician's instructions.
  • The amount of Epivir in the Epivir-HBV tablets and oral solution is less than the amount in other Epivir products used in the treatment of HIV/AIDS such as Epivir, Combivir, and Trizivir. Epivir-HBV generally should not be used by patients who have both hepatitis B and HIV infection since this may cause the HIV virus to be less treatable with Epivir and some other drugs.
  • To ensure that you get a correct dose, measure the liquid forms of Epivir with a special dose-measuring spoon or cup, not with a regular table spoon. If you NOT have a dose-measuring device, ask your pharmacist for one.
  • It is important to take Epivir regularly to get the most benefit.
  • Treatment of HIV/AIDS almost always requires the use of two or more drugs. If you need to stop taking one of the medicines you are taking for HIV, you should stop all of them until you can talk to your physician.
  • your physician may want you to have blood tests or other medical evaluations during treatment with Epivir to monitor progress and side effects.
  • Store Epivir at room temperature away from moisture and heat.

    Epivir side effects

  • Lactic acidosis and severe liver problems, including fatal cases, have been reported with the use of reverse transcriptase inhibitors, alone or in combination. Contact your physician immediately if you experience nausea, vomiting, or unusual or unexpected stomach discomfort; weakness and tiredness; shortness of breath; weakness in the arms and legs; yellowing of the skin or eyes; or pain in the upper stomach area. These may be early symptoms of lactic acidosis or liver problems.
  • Serious cases of pancreatitis (inflammation of the pancreas) have been reported with the use of Epivir. Notify your physician immediately if you develop symptoms of pancreatitis including nausea, vomiting, diarrhea, abdominal pain.
  • If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking Epivir and seek emergency medical attention.
  • Other, less serious side effects may be more likely to occur. Continue taking Epivir and talk to your physician if you experience
    -- fatigue or tiredness;
    -- mild nausea, vomiting, diarrhea, or decreased appetite;
    -- headache;
    -- insomnia;
    -- dizziness;
    -- muscle or joint soreness;
    -- fever or chills;
    -- skin rash; or
    -- redistribution of body fat (loss of fat from the arms, legs, and face and increased fat around the neck, breast, and trunk).
  • Side effects other than those listed here may also occur. Talk to your physician about any side effect that seems unusual or that is especially bothersome.

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