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  • Never take a double dose of this medication.
  • NOT take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Aleve, Anaprox), and others while taking Coumadin, except under the direction of your physician. These medicines increase the risk of bleeding.
  • Avoid sudden changes in your diet. Vitamin K decreases the effects of Coumadin. Large amounts of vitamin K are found in foods such as liver, broccoli, brussels sprouts, and green leafy vegetables (e.g., spinach, Swiss chard, coriander, collards, cabbage). NOT change the amount of these foods in your diet without first talking to your physician.
  • It will be necessary to regularly monitor your therapy with a blood test called a 'PT' or an 'INR.' These tests help to determine the amount of Coumadin that you need to take.
  • Contact your physician if you experience any unusual bruises or heavily bleeding wounds, diarrhea, infection, or fever during treatment with Coumadin.
  • Coumadin is an anticoagulant (blood thinner).
  • Coumadin reduces the formation of blood clots, which is important in the prevention of heart attacks, strokes, and blockage of major veins and arteries.
  • Coumadin may also be used for purposes other than those listed in this medication guide.




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  • Coumadin - Drug dosage. Dosage information on Coumadin

  • Take Coumadin exactly as directed by your physician. If you NOT understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • It is important to take Coumadin at the same time every day. Coumadin can be taken with or without food.
  • It is important to take Coumadin regularly to get the most benefit.
  • Never take a double dose of this medication.
  • NOT stop taking Coumadin without first talking to your physician.
  • It will be necessary to regularly monitor your therapy with a blood test called a 'PT' or an 'INR.' These tests help to determine the amount of Coumadin that you need to take. your physician may also want you to have other blood tests or medical evaluations during treatment with Coumadin to monitor progress and side effects.
  • NOT take any more or less of this drug than is prescribed for you.
  • Avoid sudden changes in your diet. Vitamin K decreases the effects of Coumadin. Large amounts of vitamin K are found in foods such as liver, broccoli, brussels sprouts, and green leafy vegetables (e.g., spinach, Swiss chard, coriander, collards, cabbage). NOT change the amount of these foods in your diet without first talking to your physician.
  • Contact your physician if you experience any unusual bruises or heavily bleeding wounds, diarrhea, infection, or fever during treatment with Coumadin.
  • Store this medication at room temperature away from moisture and heat.

    Coumadin side effects

  • If you experience any of the following serious side effects from Coumadin, stop taking the medication and seek emergency medical attention or contact your physician immediately:
    -- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
    -- black, bloody, or tarry stools;
    -- blood in urine or vomit;
    -- coughing up blood;
    -- bleeding gums or sores in the mouth;
    -- decreased urine production;
    -- yellowing of the skin or eyes;
    -- severe dizziness or headache;
    -- easy bleeding or bruising under the skin;
    -- purple discoloration of the toes or fingers;
    -- sudden leg or foot pain; or
    -- unusually heavy menstrual periods.
  • Other, less serious side effects may be more likely to occur. Talk to your physician if you experience
    -- excessive gas or bloating;
    -- diarrhea, nausea, or vomiting;
    -- hair loss; or
    -- decreased appetite or weight.
  • Side effects other than those listed here may also occur. Talk to your physician about any side effect that seems unusual or that is especially bothersome.

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