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  • NOT stop taking clonidine suddenly. This could cause severely high blood pressure, nervousness, and anxiety.
  • Use caution when driving, operating machinery, or performing other hazardous activities. Clonidine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
  • Use caution when rising from a sitting or lying position, especially first thing in the morning. You may become dizzy while taking clonidine and you may fall and injure yourself if you get up quickly.
  • NOT use alcohol, antihistamines, prescription pain relievers, sleeping pills, and other drugs that may cause drowsiness or dizziness except under the supervision of your physician.
  • Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels (veins and arteries) to relax (widen) and your heart to beat more slowly and easily.
  • Clonidine is used to treat hypertension (high blood pressure).
  • Clonidine may also be used for purposes other than those listed in this medication guide.




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  • Take clonidine exactly as directed by your physician. If you NOT understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each tablet with a full glass of water.
  • Take clonidine at bedtime unless otherwise directed by your physician. Clonidine may make you drowsy and may cause some dizziness. Taking it at bedtime may prevent falls and injuries.
  • NOT stop taking this medication suddenly even if you feel better. You may need to take clonidine for the rest of your life to control your condition.
  • Store this medication at room temperature away from moisture and heat.

    Clonidine side effects

  • If you experience any of the following serious side effects, stop taking clonidine and seek emergency medical attention:
    -- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
    -- a very slow heart rate (fewer than 60 beats per minute); or
    -- unusually high or low blood pressure (severe headache, redness of the face, neck, and chest, dizziness, and fainting).
  • Other, less serious side effects may be more likely to occur. Continue to take clonidine and talk to your physician if you experience any of the following:
    -- unusual fatigue, dizziness, or tiredness;
    -- headache;
    -- constipation, nausea, vomiting, or diarrhea;
    -- insomnia; or
    -- a dry mouth (sucking on ice chips or sugarless hard candy may relieve this side effect).
  • Side effects other than those listed here may also occur. Talk to your physician about any side effect that seems unusual or that is especially bothersome.

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